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Metossamina [DCIT]: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Metossamina [DCIT] - General Information

An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system. [PubChem]

 

Pharmacology of Metossamina [DCIT]

Metossamina [DCIT] is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metossamina [DCIT] is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metossamina [DCIT] acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.

 

Additional information about Metossamina [DCIT]

Metossamina [DCIT] Indication: Indicated for the treatment and management of hypotension. Mechanism Of Action: Metossamina [DCIT] acts through peripheral vasoconstriction by acting as a pure alpha-1 adrenergic receptor agonist, consequently increasing systemic blood pressure (both systolic and diastolic). Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Methoxamine Synonyms: Not Available Drug Category: Adrenergic alpha-Agonists; Sympathomimetics; Vasoconstrictor Agents Drug Type: Small Molecule; Approved Other Brand Names containing Methoxamine: Methoxamedrine; Methoxamin; Methoxaminum [Inn-Latin]; Metossamina [DCIT]; Metoxamina [Inn-Spanish]; Pseudomethoxamine; Vasoxine; Vasoxyl; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Low Biotransformation: Not Available Half Life: Not Available Dosage Forms of Metossamina [DCIT]: Not Available Chemical IUPAC Name: 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol Chemical Formula: C11H17NO3 Methoxamine on Wikipedia: https://en.wikipedia.org/wiki/Methoxamine Organisms Affected: Humans and other mammals