Metossamina [DCIT]
Metossamina [DCIT] - General Information
An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system. [PubChem]
Pharmacology of Metossamina [DCIT]
Metossamina [DCIT] is a potent sympathomimetic amine that increases both systolic and diastolic blood pressure. Metossamina [DCIT] is indicated for prevention and treatment of the acute hypotensive state occurring with spinal anesthesia. It is also indicated as adjunctive treatment of hypotension due to hemorrhage, reactions to medications, surgical complications, and shock associated with brain damage due to trauma or tumor. Metossamina [DCIT] acts on both α1-adrenergic receptors but appears to have no effect on β-adrenergic receptors. It acts by increasing the force of the heart's pumping action as well as constricting peripheral blood vessels.
Additional information about Metossamina [DCIT]
Metossamina [DCIT] Indication: Indicated for the treatment and management of hypotension.
Mechanism Of Action: Metossamina [DCIT] acts through peripheral vasoconstriction by acting as a pure alpha-1 adrenergic receptor agonist, consequently increasing systemic blood pressure (both systolic and diastolic).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Methoxamine
Synonyms: Not Available
Drug Category: Adrenergic alpha-Agonists; Sympathomimetics; Vasoconstrictor Agents
Drug Type: Small Molecule; Approved
Other Brand Names containing Methoxamine: Methoxamedrine; Methoxamin; Methoxaminum [Inn-Latin]; Metossamina [DCIT]; Metoxamina [Inn-Spanish]; Pseudomethoxamine; Vasoxine; Vasoxyl;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Low
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Metossamina [DCIT]: Not Available
Chemical IUPAC Name: 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
Chemical Formula: C11H17NO3
Methoxamine on Wikipedia: https://en.wikipedia.org/wiki/Methoxamine
Organisms Affected: Humans and other mammals
